STRA8 Back

stimulated by retinoic acid gene 8 homolog (mouse)

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NCBI Description of STRA8

This gene encodes a retinoic acid-responsive protein. A homologous protein in mouse has been shown to be involved in the regulation of meiotic initiation in both spermatogenesis and oogenesis, though feature differences between the mouse and human proteins suggest that these homologs are not entirely functionally equivalent. It is thought that this gene may play a role in spermatogenesis in humans.

Community Annotation of STRA8 Add / Edit STRA8: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


STRA8 is highly significantly mutated in
STRA8 is significantly mutated in
STRA8 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for STRA8