STON2 Back

stonin 2

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NCBI Description of STON2
This gene encodes a protein which is a membrane protein involved in regulating endocytotic complexes. The protein product is described as one of the clathrin-associated sorting proteins, adaptor molecules which ensure specific proteins are internalized. The encoded protein has also been shown to participate in synaptic vesicle recycling through interaction with synaptotagmin 1 required for neurotransmission. Multiple transcript variants encoding different isoforms have been found for this gene.

Community Annotation of STON2 Add / Edit STON2: Annotations

No community annotations yet for STON2.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

STON2 is highly significantly mutated in
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STON2 is significantly mutated in
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STON2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for STON2