STMN2 Back

stathmin-like 2

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NCBI Description of STMN2
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

Community Annotation of STMN2 Add / Edit STMN2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

STMN2 is highly significantly mutated in
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STMN2 is significantly mutated in
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STMN2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for STMN2