six transmembrane epithelial antigen of the prostate 1

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NCBI Description of STEAP1

This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions.

Community Annotation of STEAP1 Add / Edit STEAP1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


STEAP1 is highly significantly mutated in
STEAP1 is significantly mutated in
STEAP1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for STEAP1