STAP1 Back

signal transducing adaptor family member 1

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NCBI Description of STAP1
The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.

Community Annotation of STAP1 Add / Edit STAP1: Annotations

No community annotations yet for STAP1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

STAP1 is highly significantly mutated in
(none)
STAP1 is significantly mutated in
(none)
STAP1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for STAP1