ST8SIA6 Back

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6

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NCBI Description of ST8SIA6

Sialic acid is a key determinate of oligosaccharide structures involved in cell-cell communication, cell-substrate interaction, adhesion, and protein targeting. ST8SIA6 belongs to a family of sialyltransferases (EC 2.4.99.8) that synthesize sialylglycoconjugates (Takashima et al., 2002 [PubMed 11980897]).[supplied by OMIM, Mar 2008].

Community Annotation of ST8SIA6 Add / Edit ST8SIA6: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ST8SIA6 is highly significantly mutated in
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ST8SIA6 is significantly mutated in
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ST8SIA6 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ST8SIA6