ST8SIA2 Back

ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

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NCBI Description of ST8SIA2

The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29.

Community Annotation of ST8SIA2 Add / Edit ST8SIA2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ST8SIA2 is highly significantly mutated in
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ST8SIA2 is significantly mutated in
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ST8SIA2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for ST8SIA2