ST3GAL1 Back

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

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NCBI Description of ST3GAL1
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet.

Community Annotation of ST3GAL1 Add / Edit ST3GAL1: Annotations

No community annotations yet for ST3GAL1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

ST3GAL1 is highly significantly mutated in
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ST3GAL1 is significantly mutated in
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ST3GAL1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for ST3GAL1