SSX7 Back

synovial sarcoma, X breakpoint 7

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NCBI Description of SSX7

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation.

Community Annotation of SSX7 Add / Edit SSX7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SSX7 is highly significantly mutated in
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SSX7 is significantly mutated in
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SSX7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SSX7