SSTR3 Back

somatostatin receptor 3

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NCBI Description of SSTR3
Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biological effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR3 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in brain and pancreatic islets. SSTR3 is functionally coupled to adenylyl cyclase.

Community Annotation of SSTR3 Add / Edit SSTR3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SSTR3 is highly significantly mutated in
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SSTR3 is significantly mutated in
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SSTR3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SSTR3