SSTR2 Back

somatostatin receptor 2

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NCBI Description of SSTR2

Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SSTR2 is highly significantly mutated in
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SSTR2 is significantly mutated in
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SSTR2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SSTR2