SSTR1 Back

somatostatin receptor 1

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SSTR1
Somatostatins are peptide hormones that regulate diverse cellular functions such as neurotransmission, cell proliferation, and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins. Somatostatin has two active forms of 14 and 28 amino acids. The biological effects of somatostatins are mediated by a family of G-protein coupled somatostatin receptors that are expressed in a tissue-specific manner. The protein encoded by this gene is a member of the superfamily of somatostatin receptors having seven transmembrane segments. Somatostatin receptors form homodimers and heterodimers with other members of the superfamily as well as with other G-protein coupled receptors and receptor tyrosine kinases. This somatostatin receptor has greater affinity for somatostatin-14 than -28.

Community Annotation of SSTR1 Add / Edit SSTR1: Annotations

No community annotations yet for SSTR1.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SSTR1 is highly significantly mutated in
(none)
SSTR1 is significantly mutated in
(none)
SSTR1 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SSTR1