SSR4 Back

signal sequence receptor, delta (translocon-associated protein delta)

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NCBI Description of SSR4

This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SSR4 is highly significantly mutated in
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SSR4 is significantly mutated in
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SSR4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SSR4