SSR3 Back

signal sequence receptor, gamma (translocon-associated protein gamma)

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SSR3
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins/subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non-glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Community Annotation of SSR3 Add / Edit SSR3: Annotations

No community annotations yet for SSR3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SSR3 is highly significantly mutated in
(none)
SSR3 is significantly mutated in
(none)
SSR3 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SSR3