SSR2 Back

signal sequence receptor, beta (translocon-associated protein beta)

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NCBI Description of SSR2
The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SSR2 is highly significantly mutated in
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SSR2 is significantly mutated in
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SSR2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SSR2