SRPR Back

signal recognition particle receptor ('docking protein')

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NCBI Description of SRPR
The gene encodes a subunit of the endoplasmic reticulum signal recognition particle receptor that, in conjunction with the signal recognition particle, is involved in the targeting and translocation of signal sequence tagged secretory and membrane proteins across the endoplasmic reticulum. Alternative splicing results in multiple transcript variants.

Community Annotation of SRPR Add / Edit SRPR: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SRPR is highly significantly mutated in
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SRPR is significantly mutated in
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SRPR is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SRPR