SPSB2 Back

splA/ryanodine receptor domain and SOCS box containing 2

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NCBI Description of SPSB2
This gene encodes encodes a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants.

Community Annotation of SPSB2 Add / Edit SPSB2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SPSB2 is highly significantly mutated in
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SPSB2 is significantly mutated in
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SPSB2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SPSB2