SPAG9 Back

sperm associated antigen 9

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NCBI Description of SPAG9
This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants.

Community Annotation of SPAG9 Add / Edit SPAG9: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SPAG9 is highly significantly mutated in
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SPAG9 is significantly mutated in
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SPAG9 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SPAG9