SOX5 Back

SRY (sex determining region Y)-box 5

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NCBI Description of SOX5
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

Community Annotation of SOX5 Add / Edit SOX5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SOX5 is highly significantly mutated in
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SOX5 is significantly mutated in
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SOX5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SOX5