SOX21 Back

SRY (sex determining region Y)-box 21

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NCBI Description of SOX21
SRY-related HMG-box (SOX) genes encode a family of DNA-binding proteins containing a 79-amino acid HMG (high mobility group) domain that shares at least 50% sequence identity with the DNA-binding HMG box of the SRY protein (MIM 480000). SOX proteins are divided into 6 subgroups based on sequence similarity within and outside of the HMG domain. For additional background information on SOX genes, see SOX1 (MIM 602148).[supplied by OMIM, Apr 2004].

Community Annotation of SOX21 Add / Edit SOX21: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SOX21 is highly significantly mutated in
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SOX21 is significantly mutated in
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SOX21 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SOX21