SOCS5 Back

suppressor of cytokine signaling 5

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NCBI Description of SOCS5
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

Community Annotation of SOCS5 Add / Edit SOCS5: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SOCS5 is highly significantly mutated in
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SOCS5 is significantly mutated in
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SOCS5 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SOCS5