SNX12 Back

sorting nexin 12

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NCBI Description of SNX12
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. A similar protein in mouse may be involved in regulating the neurite outgrowth. Alternate splicing results in multiple transcript variants.

Community Annotation of SNX12 Add / Edit SNX12: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SNX12 is highly significantly mutated in
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SNX12 is significantly mutated in
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SNX12 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SNX12