SNTB1 Back

syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)

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NCBI Description of SNTB1

Dystrophin is a large, rod-like cytoskeletal protein found at the inner surface of muscle fibers. Dystrophin is missing in Duchenne Muscular Dystrophy patients and is present in reduced amounts in Becker Muscular Dystrophy patients. The protein encoded by this gene is a peripheral membrane protein found associated with dystrophin and dystrophin-related proteins. This gene is a member of the syntrophin gene family, which contains at least two other structurally-related genes. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.

Community Annotation of SNTB1 Add / Edit SNTB1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SNTB1 is highly significantly mutated in
SNTB1 is significantly mutated in
SNTB1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SNTB1