SNRPA Back

small nuclear ribonucleoprotein polypeptide A

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NCBI Description of SNRPA
The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.

Community Annotation of SNRPA Add / Edit SNRPA: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SNRPA is highly significantly mutated in
(none)
SNRPA is significantly mutated in
(none)
SNRPA is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SNRPA