SNRNP35 Back

small nuclear ribonucleoprotein 35kDa (U11/U12)

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NCBI Description of SNRNP35
The protein encoded by this gene is a homolog of U1-snRNP binding protein. The N-terminal half contains a RNA recognition motif and the C-terminal is rich in Arg/Asp and Arg/Glu dipeptides; a characteristic of a variety of splicing factors. This protein is a component of the U11/U12 small nuclear ribonucleoproteins (snRNP) that form part of the U12-type spliceosome. This gene is differentially expressed in a variety of human tissues. Alternative splicing results in multiple transcript variants encoding distinct proteins.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SNRNP35 is highly significantly mutated in
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SNRNP35 is significantly mutated in
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SNRNP35 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SNRNP35