SNRNP25 Back

small nuclear ribonucleoprotein 25kDa (U11/U12)

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NCBI Description of SNRNP25

Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 25K protein that is a component of the U12-type spliceosome.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SNRNP25 is highly significantly mutated in
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SNRNP25 is significantly mutated in
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SNRNP25 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SNRNP25