SNF8 Back

SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)

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NCBI Description of SNF8
SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741]; Kamura et al., 2001 [PubMed 11278625]).[supplied by OMIM, Mar 2008].

Community Annotation of SNF8 Add / Edit SNF8: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SNF8 is highly significantly mutated in
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SNF8 is significantly mutated in
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SNF8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SNF8