SNAI1 Back

snail homolog 1 (Drosophila)

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NCBI Description of SNAI1

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SNAI1 is highly significantly mutated in
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SNAI1 is significantly mutated in
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SNAI1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SNAI1