SMARCC1 Back

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

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NCBI Description of SMARCC1
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.

Community Annotation of SMARCC1 Add / Edit SMARCC1: Annotations

No community annotations yet for SMARCC1.
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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SMARCC1 is highly significantly mutated in
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SMARCC1 is significantly mutated in
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SMARCC1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SMARCC1