SMARCAD1 Back

SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1

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NCBI Description of SMARCAD1
This gene encodes a member of the SNF subfamily of helicase proteins. The encoded protein plays a critical role in the restoration of heterochromatin organization and propagation of epigenetic patterns following DNA replication by mediating histone H3/H4 deacetylation. Mutations in this gene are associated with adermatoglyphia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Community Annotation of SMARCAD1 Add / Edit SMARCAD1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SMARCAD1 is highly significantly mutated in
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SMARCAD1 is significantly mutated in
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SMARCAD1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SMARCAD1