SLITRK4 Back

SLIT and NTRK-like family, member 4

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NCBI Description of SLITRK4

This gene encodes a transmembrane protein belonging to the the SLITRK family. These family members include two N-terminal leucine-rich repeat domains similar to those found in the axonal growth-controlling protein SLIT, as well as C-terminal regions similar to neurotrophin receptors. Studies of an homologous protein in mouse suggest that this family member functions to suppress neurite outgrowth. Alternative splicing results in multiple transcript variants.

Community Annotation of SLITRK4 Add / Edit SLITRK4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLITRK4 is highly significantly mutated in
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SLITRK4 is significantly mutated in
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SLITRK4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLITRK4