SLIT and NTRK-like family, member 3

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SLITRK3

Members of the SLITRK family, such as SLITRK3, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK3, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM, Mar 2008].

Community Annotation of SLITRK3 Add / Edit SLITRK3: Annotations

No community annotations yet for SLITRK3.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SLITRK3 is highly significantly mutated in
SLITRK3 is significantly mutated in
SLITRK3 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SLITRK3