SLC9A8 Back

solute carrier family 9 (sodium/hydrogen exchanger), member 8

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NCBI Description of SLC9A8
Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008 [PubMed 18209477]).[supplied by OMIM, Apr 2009].

Community Annotation of SLC9A8 Add / Edit SLC9A8: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC9A8 is highly significantly mutated in
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SLC9A8 is significantly mutated in
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SLC9A8 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC9A8