SLC9A7 Back

solute carrier family 9 (sodium/hydrogen exchanger), member 7

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NCBI Description of SLC9A7
This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants.

Community Annotation of SLC9A7 Add / Edit SLC9A7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC9A7 is highly significantly mutated in
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SLC9A7 is significantly mutated in
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SLC9A7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC9A7