SLC9A1 Back

solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive)

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NCBI Description of SLC9A1

This gene encodes a Na+/H+ antiporter that is a member of the solute carrier family 9. The encoded protein is a plasma membrane transporter that is expressed in the kidney and intestine. This protein plays a central role in regulating pH homeostasis, cell migration and cell volume. This protein may also be involved in tumor growth.

Community Annotation of SLC9A1 Add / Edit SLC9A1: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SLC9A1 is highly significantly mutated in
SLC9A1 is significantly mutated in
SLC9A1 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SLC9A1