SLC6A11 Back

solute carrier family 6 (neurotransmitter transporter, GABA), member 11

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NCBI Description of SLC6A11

Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter. GABAergic neurotransmission is terminated by the uptake of GABA into the presynaptic terminal and the surrounding astroglial cells by sodium-dependent transporters, such as SLC6A11 (Borden et al., 1994 [PubMed 7874447]).[supplied by OMIM, Nov 2010].

Community Annotation of SLC6A11 Add / Edit SLC6A11: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SLC6A11 is highly significantly mutated in
SLC6A11 is significantly mutated in
SLC6A11 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SLC6A11