SLC5A7 Back

solute carrier family 5 (choline transporter), member 7

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NCBI Description of SLC5A7
Choline is a direct precursor of acetylcholine (ACh), a neurotransmitter of the central and peripheral nervous system that regulates a variety of autonomic, cognitive, and motor functions. SLC5A7 is a Na(+)- and Cl(-)- dependent high-affinity transporter that mediates the uptake of choline for acetylcholine synthesis in cholinergic neurons (Apparsundaram et al., 2000 [PubMed 11027560]).[supplied by OMIM, Mar 2008].

Community Annotation of SLC5A7 Add / Edit SLC5A7: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC5A7 is highly significantly mutated in
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SLC5A7 is significantly mutated in
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SLC5A7 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC5A7