SLC5A5 Back

solute carrier family 5 (sodium iodide symporter), member 5

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SLC5A5
This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.

Community Annotation of SLC5A5 Add / Edit SLC5A5: Annotations

No community annotations yet for SLC5A5.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC5A5 is highly significantly mutated in
(none)
SLC5A5 is significantly mutated in
(none)
SLC5A5 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC5A5