SLC4A8 Back

solute carrier family 4, sodium bicarbonate cotransporter, member 8

External References:      Wikipedia GeneCards HUGO COSMIC Google Scholar

NCBI Description of SLC4A8
The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene.

Community Annotation of SLC4A8 Add / Edit SLC4A8: Annotations

No community annotations yet for SLC4A8.
Sort mutations by: Tumor type  Mutation type  Position  
Straightedge cursor Expand

Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC4A8 is highly significantly mutated in
(none)
SLC4A8 is significantly mutated in
(none)
SLC4A8 is near significance in
(none)

Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC4A8