SLC4A7 Back

solute carrier family 4, sodium bicarbonate cotransporter, member 7

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NCBI Description of SLC4A7

This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical role in regulation of intracellular pH involved in visual and auditory sensory transmission. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Community Annotation of SLC4A7 Add / Edit SLC4A7: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SLC4A7 is highly significantly mutated in
SLC4A7 is significantly mutated in
SLC4A7 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SLC4A7