SLC47A2 Back

solute carrier family 47, member 2

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NCBI Description of SLC47A2
This gene encodes a protein belonging to a family of transporters involved in excretion of toxic electrolytes, both endogenous and exogenous, through urine and bile. This transporter family shares homology with the bacterial MATE (multidrug and toxin extrusion) protein family responsible for drug resistance. This gene is one of two members of the MATE transporter family located near each other on chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Community Annotation of SLC47A2 Add / Edit SLC47A2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC47A2 is highly significantly mutated in
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SLC47A2 is significantly mutated in
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SLC47A2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC47A2