SLC3A2 Back

solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2

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NCBI Description of SLC3A2

This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Community Annotation of SLC3A2 Add / Edit SLC3A2: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SLC3A2 is highly significantly mutated in
SLC3A2 is significantly mutated in
SLC3A2 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SLC3A2