SLC39A12 Back

solute carrier family 39 (zinc transporter), member 12

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NCBI Description of SLC39A12

Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A12 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Aug 2008].

Community Annotation of SLC39A12 Add / Edit SLC39A12: Annotations

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Figure notes

• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


SLC39A12 is highly significantly mutated in
SLC39A12 is significantly mutated in
SLC39A12 is near significance in

Click on a tumor type to see its full list of significant genes.

Data details

Mutation list for SLC39A12