SLC38A1 Back

solute carrier family 38, member 1

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NCBI Description of SLC38A1
Amino acid transporters play essential roles in the uptake of nutrients, production of energy, chemical metabolism, detoxification, and neurotransmitter cycling. SLC38A1 is an important transporter of glutamine, an intermediate in the detoxification of ammonia and the production of urea. Glutamine serves as a precursor for the synaptic transmitter, glutamate (Gu et al., 2001 [PubMed 11325958]).[supplied by OMIM, Mar 2008].

Community Annotation of SLC38A1 Add / Edit SLC38A1: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC38A1 is highly significantly mutated in
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SLC38A1 is significantly mutated in
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SLC38A1 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC38A1