SLC36A4 Back

solute carrier family 36 (proton/amino acid symporter), member 4

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NCBI Description of SLC36A4
SLC36A4 belongs to the SLC36 family of amino acid transporters based on sequence similarity with other family members (e.g., SLC36A1; MIM 606561). SLC36 proteins contain about 500 amino acids and have 9 to 11 transmembrane domains. Unlike other SLC36 family members, which are proton-coupled amino acid transporters, SLC36A4 is a high-affinity/low-capacity non-proton-coupled amino acid transporter (Pillai and Meredith, 2011 [PubMed 21097500]).[supplied by OMIM, Feb 2011].

Community Annotation of SLC36A4 Add / Edit SLC36A4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC36A4 is highly significantly mutated in
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SLC36A4 is significantly mutated in
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SLC36A4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC36A4