SLC35C2 Back

solute carrier family 35, member C2

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NCBI Description of SLC35C2

Oxygenation levels play an important role in the regulation of cellular invasiveness which occurs during early implantation when the trophoblast cells invade the uterus as well as during tumour progression and metastasis. This gene, which is regulated by oxygen tension, is induced in hypoxic trophoblast cells and is overexpressed in ovarian cancer. Two protein isoforms are encoded by transcript variants of this gene.

Community Annotation of SLC35C2 Add / Edit SLC35C2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC35C2 is highly significantly mutated in
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SLC35C2 is significantly mutated in
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SLC35C2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC35C2