SLC35B3 Back

solute carrier family 35, member B3

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NCBI Description of SLC35B3

Sulfation of a variety of molecules, including glycoproteins, proteoglycans, and glycolipids, requires 3-prime phosphoadenosine 5-prime phosphosulfate (PAPS), a high-energy form of the universal sulfate donor. SLC35B3 translocates PAPS from the cytosol or nucleus, where it is synthesized, to the Golgi lumen for use (Kamiyama et al., 2006 [PubMed 16492677]).[supplied by OMIM, Mar 2008].

Community Annotation of SLC35B3 Add / Edit SLC35B3: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC35B3 is highly significantly mutated in
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SLC35B3 is significantly mutated in
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SLC35B3 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC35B3