SLC2A4 Back

solute carrier family 2 (facilitated glucose transporter), member 4

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NCBI Description of SLC2A4
This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC2A4 is highly significantly mutated in
(none)
SLC2A4 is significantly mutated in
(none)
SLC2A4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC2A4