SLC29A4 Back

solute carrier family 29 (nucleoside transporters), member 4

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NCBI Description of SLC29A4
This gene is a member of the SLC29 family and encodes a plasma membrane protein with 11 transmembrane helices. This protein catalyzes the reuptake of monoamines into presynaptic neurons, thus determining the intensity and duration of monoamine neural signaling. It has been shown to transport several compounds, including serotonin, dopamine, and the neurotoxin 1-methyl-4-phenylpyridinium. Alternate transcriptional splice variants which encode the same protein have been characterized.

Community Annotation of SLC29A4 Add / Edit SLC29A4: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC29A4 is highly significantly mutated in
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SLC29A4 is significantly mutated in
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SLC29A4 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


• Mutation list for SLC29A4