SLC29A2 Back

solute carrier family 29 (nucleoside transporters), member 2

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NCBI Description of SLC29A2

The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008].

Community Annotation of SLC29A2 Add / Edit SLC29A2: Annotations

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Figure notes


• "Mouse over" a mutation to see details.
• Missense green saturation indicates evolutionary conservation of the mutated positions.
• Red hashes in protein strip are splice sites.
• Blue-white-red bars are log2 copy ratio distributions (–1 to +1) from Zack et al. (2013).


Legend

SLC29A2 is highly significantly mutated in
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SLC29A2 is significantly mutated in
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SLC29A2 is near significance in
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Click on a tumor type to see its full list of significant genes.

Data details


Mutation list for SLC29A2